Maternal exposure to hydroxychloroquine and birth defects.

ABSTRACT:

Background

Hydroxychloroquine is a treatment for rheumatic disease and considered safe during pregnancy. Interest in hydroxychloroquine has increased as it is being examined as a potential treatment and prophylaxis for coronavirus disease 2019. Data on the risks of specific birth defects associated with hydroxychloroquine use are sparse.

Methods

Using data from two case-control studies (National Birth Defects Prevention Study and Slone Epidemiology Center Birth Defects Study), we described women who reported hydroxychloroquine use in pregnancy and the presence of specific major birth defects in their offspring. Cases had at least one major birth defect and controls were live-born healthy infants. Women self-reported medication use information in the few months before pregnan

SUBMITTER: Howley MM 

PROVIDER: S-EPMC8426694 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature