Left ventricular-only fusion pacing versus cardiac resynchronization therapy in heart failure patients: A randomized controlled trial.

ABSTRACT:

Background

It is unclear whether clinical benefits of cardiac resynchronization can be achieved by pacing only the left ventricle.

Hypothesis

We aimed to compare the effect of a novel adaptive left ventricular-only fusion pacing (LVP) on ventricular function with conventional biventricular pacing (BVP) in cardiac resynchronization therapy (CRT) indicated patients.

Methods

This prospective, randomized, multicenter study enrolled CRT-indicated patients with PR interval ≤ 200 ms who were randomized in the adaptive LVP group (using the AdaptivCRT™ algorithm with intentional non-capture right ventricular pacing) or the echocardiography-optimized BVP group. Cardiac function and echocardiography were evaluated at baseline and follow-ups. CRT super response was defined as two

SUBMITTER: Su Y 

PROVIDER: S-EPMC8427977 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature