Longitudinal association between cognitive depressive symptoms and D-dimer levels in patients following acute myocardial infarction.

ABSTRACT:

Background

A prothrombotic tendency could partially explain the poor prognosis of patients with coronary heart disease and depression. We hypothesized that cognitive depressive symptoms are positively associated with the coagulation activation marker D-dimer throughout the first year after myocardial infarction (MI).

Methods

Patients with acute MI (mean age 60 years, 85% men) were investigated at hospital admission (n = 190), 3 months (n = 154) and 12 months (n = 106). Random linear mixed regression models were used to evaluate the relation between cognitive depressive symptoms, assessed with the Beck depression inventory (BDI), and changes in plasma D-dimer levels. Demographics, cardiac disease severity, medical comorbidity, depression history, medication, health behaviors,

SUBMITTER: von Kanel R 

PROVIDER: S-EPMC8428069 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature