Biomarker in Active Surveillance for Prostate Cancer: A Systematic Review.

ABSTRACT: Active surveillance (AS) in prostate cancer (PCa) represents a curative alternative for men with localised low-risk PCa. Continuous improvement of AS patient's selection and surveillance modalities aims at reducing misclassification, simplifying modalities of surveillance and decreasing need for invasive procedures such repeated biopsies. Biomarkers represent interesting tools to evaluate PCa diagnosis and prognosis, of which many are readily available or under evaluation. The aim of this review is to investigate the biomarker performance for AS selection and patient outcome prediction. Blood, urinary and tissue biomarkers were studied and a brief description of use was proposed along with a summary of major findings. Biomarkers represent promising tools which could be part of a more tailo

SUBMITTER: Manceau C 

PROVIDER: S-EPMC8428218 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature