Sucrose Intakes and Incident Colorectal Cancer Risk among Women.

ABSTRACT:

Background

High sucrose intakes are hypothesized to increase colorectal cancer (CRC) risk by several mechanisms, and sucrose intakes have been consistently positively associated with CRC risk in case-control studies. However, all but one prospective study reported a null sucrose-CRC association. The only prospective study to report a positive association was the Iowa Women's Health Study (IWHS) of 35,221 cancer-free Iowa women, aged 55 - 69 years old at baseline in 1986, after four years of follow up.

Materials and methods

To address the discrepant findings in the literature, after 26 years of follow up in the IWHS, we updated and expanded on our earlier reported analyses. During follow up through 2012, 1,731 women were diagnosed with CRC. Baseline dietary intakes were asses

SUBMITTER: Kiran N 

PROVIDER: S-EPMC8428539 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature