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Vascular endothelial growth factor (VEGF) targeting therapy for persistent, recurrent, or metastatic cervical cancer.


ABSTRACT:

SUBMITTER: Chuai Y 

PROVIDER: S-EPMC8428759 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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Vascular endothelial growth factor (VEGF) targeting therapy for persistent, recurrent, or metastatic cervical cancer.

Chuai Yunhai Y   Rizzuto Ivana I   Zhang Xia X   Li Ying Y   Dai Guanghai G   Otter Sophie J SJ   Bharathan Rasiah R   Stewart Alexandra A   Wang Aiming A  

The Cochrane database of systematic reviews 20210304


<h4>Background</h4>Cervical cancer ranks as the fourth leading cause of death from cancer in women. Historically, women with metastatic or recurrent cervical cancer have had limited treatment options. New anti-angiogenesis therapies, such as vascular endothelial growth factor (VEGF) targeting agents, offer an alternative strategy to conventional chemotherapy; they act by inhibiting the growth of new blood vessels, thereby restricting tumour growth by blocking the blood supply.<h4>Objectives</h4>  ...[more]

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