Prefrontal Lesions Disrupt Posterior Alpha-Gamma Coordination of Visual Working Memory Representations.

ABSTRACT: How does the human brain prioritize different visual representations in working memory (WM)? Here, we define the oscillatory mechanisms supporting selection of "where" and "when" features from visual WM storage and investigate the role of pFC in feature selection. Fourteen individuals with lateral pFC damage and 20 healthy controls performed a visuospatial WM task while EEG was recorded. On each trial, two shapes were presented sequentially in a top/bottom spatial orientation. A retro-cue presented mid-delay prompted which of the two shapes had been in either the top/bottom spatial position or first/second temporal position. We found that cross-frequency coupling between parieto-occipital alpha (α; 8-12 Hz) oscillations and topographically distributed gamma (γ; 30-50 Hz) activity tracked s

SUBMITTER: Davoudi S 

PROVIDER: S-EPMC8428813 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature