Gut Microbiota in Psychiatric Disorders: A Systematic Review.

ABSTRACT:

Objective

This systematic review sought to comprehensively summarize gut microbiota research in psychiatric disorders following PRISMA guidelines.

Methods

Literature searches were performed on databases using keywords involving gut microbiota and psychiatric disorders. Articles in English with human participants up until February 13, 2020, were reviewed. Risk of bias was assessed using a modified Newcastle-Ottawa Scale for microbiota studies.

Results

Sixty-nine of 4231 identified studies met the inclusion criteria for extraction. In most studies, gut microbiota composition differed between individuals with psychiatric disorders and healthy controls; however, limited consistency was observed in the taxonomic profiles. At the genus level, the most replicated findings we

SUBMITTER: Chen LL 

PROVIDER: S-EPMC8428865 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature