Brain, behavioral, affective, and sex correlates of recovery from alcohol use disorders.

ABSTRACT:

Background

Recovery from alcohol use disorders (AUDs) consists of salutary changes in behavior and affect. While evidence suggests that recovery-related behavioral changes, such as abstinence, emerge in tandem with both neural and affective changes, the precise relationships among these changes are unknown. To understand these relationships, we examined associations between the duration of abstinence (DOA), affective states, and neuroimaging-based structural measures of the brain reward system (BRS) in AUD men (AUD_M ) and AUD women (AUD_W ).

Methods

Participants were community respondents from the Boston area comprising right-handed abstinent individuals with AUD (n = 60; 30 men) and controls without AUD (NC; n = 60; 29 men). Multivariate linear regressi

SUBMITTER: Thompson BL 

PROVIDER: S-EPMC8429096 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature