Focal limbic sources create the large slow oscillations of the EEG in human deep sleep.

ABSTRACT:

Background

Initial observations with the human electroencephalogram (EEG) have interpreted slow oscillations (SOs) of the EEG during deep sleep (N3) as reflecting widespread surface-negative traveling waves that originate in frontal regions and propagate across the neocortex. However, mapping SOs with a high-density array shows the simultaneous appearance of posterior positive voltage fields in the EEG at the time of the frontal-negative fields, with the typical inversion point (apparent source) around the temporal lobe.

Methods

Overnight 256-channel EEG recordings were gathered from 10 healthy young adults. Individual head conductivity models were created using each participant's own structural MRI. Source localization of SOs during N3 was then performed.

Results

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SUBMITTER: Morgan KK 

PROVIDER: S-EPMC8429272 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature