Titanium carbide nanosheets with defect structure for photothermal-enhanced sonodynamic therapy.

ABSTRACT: Sonodynamic therapy (SDT) has attracted widespread interest in biomedicine, owing to its novel and noninvasive therapeutic method triggered by ultrasound (US). Herein, the Ti₃C₂ MXene nanosheets (Ti₃C₂ NSs) are developed as good sonosensitizers via a two-step method of chemical exfoliation and high-temperature treatment. With the high-temperature treatment, the oxygen defect of Ti₃C₂ MXene nanosheets (H-Ti₃C₂ NSs) is greatly increased. Therefore, the electron (e^-) and hole (h⁺) generated by US can be separated faster due to the improved degree of oxidation, and then the recombination of e^--h⁺ can be prevented with the abundant oxygen defect under US irradiatio

SUBMITTER: Li G 

PROVIDER: S-EPMC8429621 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature