Acoustofluidic localization of sparse particles on a piezoelectric resonant sensor for nanogram-scale mass measurements.

ABSTRACT: The ability to weigh microsubstances present in low concentrations is an important tool for environmental monitoring and chemical analysis. For instance, developing a rapid analysis platform that identifies the material type of microplastics in seawater would help evaluate the potential toxicity to marine organisms. In this study, we demonstrate the integration of two different techniques that bring together the functions of sparse particle localization and miniaturized mass sensing on a microelectromechanical system (MEMS) chip for enhanced detection and minimization of negative measurements. The droplet sample for analysis is loaded onto the MEMS chip containing a resonant mass sensor. Through the coupling of a surface acoustic wave (SAW) from a SAW transducer into the chip, the initiall

SUBMITTER: Qian J 

PROVIDER: S-EPMC8433202 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature