A 3D-printed modular magnetic digital microfluidic architecture for on-demand bioanalysis.

ABSTRACT: Magnetic digital microfluidics (MDM) manipulates fluids in the form of droplets on an open substrate, and incorporates surface energy traps (SETs) to facilitate the droplet manipulation. Conventional MDM devices are fabricated monolithically, which makes it difficult to modify the device configuration without completely overhauling the original design. In this paper, we present a modular MDM architecture that enables rapid on-demand configuration and re-configuration of MDM platforms for customized bioanalyses. Each modular component contains a SET and a Lego-like antistud that fits onto a base board with Lego-like studs. We illustrate the versatility of the modular MDM architecture in biomarker sensing, pathogen identification, antibiotic resistance determination, and biochemical quantifi

SUBMITTER: Kanitthamniyom P 

PROVIDER: S-EPMC8433373 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature