Sliding walls: a new paradigm for fluidic actuation and protocol implementation in microfluidics.

ABSTRACT: Currently, fluidic control in microdevices is mainly achieved either by external pumps and valves, which are expensive and bulky, or by valves integrated in the chip. Numerous types of internal valves or actuation methods have been proposed, but they generally impose difficult compromises between performance and fabrication complexity. We propose here a new paradigm for actuation in microfluidic devices based on rigid or semi-rigid walls with transversal dimensions of hundreds of micrometres that are able to slide within a microfluidic chip and to intersect microchannels with hand-driven or translation stage-based actuation. With this new concept for reconfigurable microfluidics, the implementation of a wide range of functionalities was facilitated and allowed for no or limited dead volume

SUBMITTER: Venzac B 

PROVIDER: S-EPMC8433466 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature