High-Resolution Bioprinting of Recombinant Human Collagen Type III.

ABSTRACT: The development of commercial collagen inks for extrusion-based bioprinting has increased the amount of research on pure collagen bioprinting, i.e., collagen inks not mixed with gelatin, alginate, or other more common biomaterial inks. New printing techniques have also improved the resolution achievable with pure collagen bioprinting. However, the resultant collagen constructs still appear too weak to replicate dense collagenous tissues, such as the cornea. This work aims to demonstrate the first reported case of bioprinted recombinant collagen films with suitable optical and mechanical properties for corneal tissue engineering. The printing technology used, aerosol jet^® printing (AJP), is a high-resolution printing method normally used to deposit conductive inks for electronic

SUBMITTER: Gibney R 

PROVIDER: S-EPMC8434404 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature