Data driven patterns of nutrient intake and coronary artery disease risk in adults with type 1 diabetes.

ABSTRACT:

Aims

Dietary intake provides a potential intervention target to reduce the high risk for coronary artery disease (CAD) in type 1 diabetes. This effort aimed to identify patterns of nutrient intake in young/middle-aged adults with type 1 diabetes and to examine associations between those patterns and development of CAD.

Methods

Principal component analysis was used to derive nutrient intake patterns among 514 individuals with childhood-onset (<17 years old) type 1 diabetes aged 18+ years and free of CAD (defined as CAD death, myocardial infarction, revascularization, ischemia, or study physician diagnosed angina). Cox models were used to assess the association between nutrient patterns and CAD incidence over 30-years of follow-up.

Results

Three nutrient principal compo

SUBMITTER: Devaraj SM 

PROVIDER: S-EPMC8434996 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature