Roux-en-Y Gastric Bypass Is Associated With Increased Hazard for De Novo Alcohol-related Complications and Liver Disease.

ABSTRACT:

Goal

The goal of this study was to determine if bariatric surgeries are associated with de novo alcohol-related complications.

Background

Bariatric surgery is associated with an increased risk of alcohol use disorders. The effect of bariatric surgeries on other alcohol-related outcomes, including liver disease, is understudied.

Materials and methods

Using the IMS PharMetrics database, we performed a cohort study of adults undergoing bariatric surgery or cholecystectomy, excluding patients with an alcohol-related diagnosis within 1 year before surgery. The primary outcome was any alcohol-related diagnosis after surgery. We fit a multivariable Cox proportional hazards model to determine independent associations between bariatric surgeries [Roux-en-Y gastric bypass (RYGB

SUBMITTER: Kim HP 

PROVIDER: S-EPMC8435050 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature