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Methodological challenges for living systematic reviews conducted during the COVID-19 pandemic: A concept paper.


ABSTRACT:

Background

A living systematic review (LSR) is an emerging review type that makes use of continual updating. In the COVID-19 pandemic, we were confronted with a shifting epidemiological landscape, clinical uncertainties and evolving evidence. These unexpected challenges compelled us to amend standard LSR methodology.

Objective and outline

Our primary objective is to discuss some challenges faced when conducting LSRs in the context of the COVID-19 pandemic, and to provide methodological guidance for others doing similar work. Based on our experience and lessons learned from two Cochrane LSRs and challenges identified in several non-Cochrane LSRs, we highlight methodological considerations, particularly with regards to the study design, interventions and comparators, changes i

SUBMITTER: Iannizzi C 

PROVIDER: S-EPMC8435072 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature