Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women.

ABSTRACT:

Aims/hypothesis

In our current society sedentary behaviour predominates in most people and is associated with the risk of developing type 2 diabetes. It has been suggested that replacing sitting time by standing and walking could be beneficial for individuals with type 2 diabetes but the underlying mechanisms are unknown and direct comparisons with exercise are lacking. Our objective was to directly compare metabolic responses of either sitting less or exercising, relative to being sedentary.

Methods

We performed a randomised, crossover intervention study in 12 overweight women who performed three well-controlled 4 day activity regimens: (1) sitting regimen (sitting 14 h/day); (2) exercise regimen (sitting 13 h/day, exercise 1 h/day); and (3) sitting less regimen (sitting 9 

SUBMITTER: Remie CME 

PROVIDER: S-EPMC8435176 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature