Cbl upregulates cysH for hydrogen sulfide production in Aeromonas veronii.

ABSTRACT: Endogenous hydrogen sulfide (H₂S) is generated in many metabolism pathways, and has been recognized as a second messenger against antibiotics and reactive oxygen species (ROS). In Aeromonas veronii, Small Protein B (SmpB) plays an important role in resisting stress. The absence of smpB could trigger sulfate assimilation pathway to adapt the nutrient deficiency, of which was mediated by up-regulation of cbl and cys genes and followed with enhancing H₂S production. To figure out the mutual regulations of cbl and cys genes, a series of experiments were performed. Compared with the wild type, cysH was down-regulated significantly in cbl deletion by qRT-PCR. The fluorescence analysis further manifested that Cbl had a

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC8435198 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature