Southern rice black-streaked dwarf virus hijacks SNARE complex of its insect vector for its effective transmission to rice.

ABSTRACT: Vesicular trafficking is an important dynamic process that facilitates intracellular transport of biological macromolecules and their release into the extracellular environment. However, little is known about whether or how plant viruses utilize intracellular vesicles to their advantage. Here, we report that southern rice black-streaked dwarf virus (SRBSDV) enters intracellular vesicles in epithelial cells of its insect vector by engaging VAMP7 and Vti1a proteins in the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex. The major outer capsid protein P10 of SRBSDV was shown to interact with VAMP7 and Vti1a of the white-backed planthopper and promote the fusion of vesicles into a large vesicle, which finally fused with the plasma membrane to release virio

SUBMITTER: Zhang L 

PROVIDER: S-EPMC8435234 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature