Ontology highlight
ABSTRACT:
SUBMITTER: Lee ES
PROVIDER: S-EPMC8435425 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Lee Eun Soo ES Kang Jeong Suk JS Kim Hong Min HM Kim Su Jin SJ Kim Nami N Lee Jung Ok JO Kim Hyeon Soo HS Lee Eun Young EY Chung Choon Hee CH
Journal of cellular and molecular medicine 20210812 18
Ectopic fat accumulation in the kidneys causes oxidative stress, inflammation and cell death. Dehydrozingerone (DHZ) is a curcumin analog that exhibits antitumour, antioxidant and antidiabetic effects. However, the efficacy of DHZ in diabetic nephropathy (DN) is unknown. Here, we verified the efficacy of DHZ on DN. We divided the experimental animals into three groups: regular diet, 60% high-fat diet (HFD) and HFD with DHZ for 12 weeks. We analysed levels of renal triglycerides and urinary album ...[more]