A radiomics-based nomogram for preoperative T staging prediction of rectal cancer.

ABSTRACT:

Purpose

To investigate the value of a radiomics-based nomogram in predicting preoperative T staging of rectal cancer.

Methods

A total of 268 eligible rectal cancer patients from August 2012 to December 2018 were enrolled and allocated into two datasets: training (n = 188) and validation datasets (n = 80). Another set of 32 patients from January 2019 to July 2019 was included in a prospective analysis. Pretreatment T2-weighted images were used to radiomics features extraction. Feature selection and radiomics score (Rad-score) construction were performed through a least absolute shrinkage and selection operator regression analysis. The nomogram, which included Rad-scores and clinical factors, was built using multivariate logistic regression. Discrimination, calibration, and cl

SUBMITTER: Lin X 

PROVIDER: S-EPMC8435521 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature