Glucose Intolerance and Cancer Risk: A Community-Based Prospective Cohort Study in Shanghai, China.

ABSTRACT:

Background

Cancer becomes the leading cause of premature death in China. Primary objective of this study was to determine the major risk factors especially glucose intolerance for cancer prophylaxis.

Methods

A cluster sampling method was applied to enroll 10,657 community-based adults aged 15-92 years in Shanghai, China in 2013. A structured questionnaire and physical examination were applied in baseline survey. Prediabetes was diagnosed using 75-g oral glucose tolerance test. After excluding 1433 subjects including 224 diagnosed with cancer before and 1 year after baseline survey, the remaining 9,224 subjects were followed-up to December 31, 2020.

Results

A total of 502 new cancer cases were diagnosed. The cancer incidence was 10.29, 9.20, and 5.95/1,000 person-years

SUBMITTER: Ke J 

PROVIDER: S-EPMC8435720 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature