Natural Products as Potential Lead Compounds for Drug Discovery Against SARS-CoV-2.

ABSTRACT: For the past 2 years, the coronavirus responsible for the COVID-19 infection has become a world pandemic, ruining the lives and economies of several nations in the world. This has scaled up research on the virus and the resulting infection with the goal of developing new vaccines and therapies. Natural products are known to be a rich source of lead compounds for drug discovery, including against infectious diseases caused by microbes (viruses, bacteria and fungi). In this review article, we conducted a literature survey aimed at identifying natural products with inhibitory concentrations against the coronaviruses or their target proteins, which lie below 10 µM. This led to the identification of 42 compounds belonging to the alkaloid, flavonoid, terpenoid, phenolic, xanthone and saponin cla

SUBMITTER: Ebob OT 

PROVIDER: S-EPMC8435765 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature