Retinal Diseases and Parkinson Disease: A Population-Based Study.

ABSTRACT:

Introduction

Patients with Parkinson disease (PD) tend to have ophthalmic symptoms. Retinal diseases are associated with central nervous system diseases, especially neurodegenerative diseases. Here, we investigated the association of retinal diseases with PD, especially the temporal relationship before and after PD diagnosis.

Methods

Data were obtained from the National Health Insurance Research Database of Taiwan. In total, 21,845 patients with newly diagnosed PD were matched with four controls each on the basis of propensity score. This study was bidirectional. A case-control study evaluated the adjusted odds ratio (aOR) of retinal disease before PD diagnosis by using conditional logistic regression. Furthermore, a cohort study evaluated the adjusted subdistribution hazard

SUBMITTER: Chen PC 

PROVIDER: S-EPMC8435857 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature