The Association of Human Leukocyte Antigen and COVID-19 in Southern China.

ABSTRACT: Human leukocyte antigen (HLA) polymorphism is hypothesized to be associated with diverse immune responses toward infectious diseases. Herein, by comparing against multiple subpopulation groups as control, we confirmed that HLA-B*15:27 and HLA-DRB1*04:06 were associated with coronavirus disease 2019 susceptibility in China. Both alleles were predicted to have weak binding affinities toward viral proteins.

SUBMITTER: Yu X 

PROVIDER: S-EPMC8436377 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature