The Association of Human Leukocyte Antigen and COVID-19 in Southern China.
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ABSTRACT:
SUBMITTER: Yu X
PROVIDER: S-EPMC8436377 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Publications
The Association of Human Leukocyte Antigen and COVID-19 in Southern China.
Yu Xueping X Ho Kuoting K Shen Zhongliang Z Fu Xiaoying X Huang Hongbo H Wu Delun D Lin Yancheng Y Lin Yijian Y Chen Wenhuang W Su Milong M Qiu Chao C Zhuang Xibin X Su Zhijun Z
Open forum infectious diseases 20210806 9
Human leukocyte antigen (HLA) polymorphism is hypothesized to be associated with diverse immune responses toward infectious diseases. Herein, by comparing against multiple subpopulation groups as control, we confirmed that HLA-B*15:27 and HLA-DRB1*04:06 were associated with coronavirus disease 2019 susceptibility in China. Both alleles were predicted to have weak binding affinities toward viral proteins. ...[more]
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