Complete genome sequence and identification of polyunsaturated fatty acid biosynthesis genes of the myxobacterium Minicystis rosea DSM 24000^T.

ABSTRACT:

Background

Myxobacteria harbor numerous biosynthetic gene clusters that can produce a diverse range of secondary metabolites. Minicystis rosea DSM 24000^T is a soil-dwelling myxobacterium belonging to the suborderSorangiineae and family Polyangiaceae and is known to produce various secondary metabolites as well as polyunsaturated fatty acids (PUFAs). Here, we use whole-genome sequencing to explore the diversity of biosynthetic gene clusters in M. rosea.

Results

Using PacBio sequencing technology, we assembled the 16.04 Mbp complete genome of M. rosea DSM 24000^T, the largest bacterial genome sequenced to date. About 44% of its coding potential represents paralogous genes predominantly associated with signal transduction, transcriptional regulation, and pr

SUBMITTER: Pal S 

PROVIDER: S-EPMC8436480 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature