Neuromuscular block in patients 80 years and older: a prospective, controlled study.

ABSTRACT:

Background

An increasing number of patients older than 80 years are undergoing anesthesia, but little information is available regarding pharmacodynamic effects of myorelaxants in this population. This study aims to compare the time course of rocuronium neuromuscular block in patients ≥ 80 years with those of younger adults.

Methods

Under total intravenous anesthesia with propofol and sufentanil, time course of a bolus of rocuronium 0.6 mg/kg neuromuscular block was assessed with acceleromyography in patients ≥ 80 and in patients 20-50 years old. Onset time, clinical duration, duration until 90% and 100% recovery of baseline were determined.

Results

Data from 32 patients were analyzed, 16 were ≥ 80 years and 16 were 20-50 years old. Demographic data are shown in Table

SUBMITTER: Schmartz D 

PROVIDER: S-EPMC8436544 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature