Treponema pallidum in female sex workers from the Brazilian Marajo Archipelago: prevalence, risk factors, drug-resistant mutations and coinfections.

ABSTRACT:

Background

Female sex workers (FSWs) are an especially vulnerable group for syphilis and other sexually transmitted infection (STIs). This study determined the prevalence of syphilis in FSWs and factors associated with this disease in the Marajó Archipelago (northern Brazil), as well as the frequency of point mutations (A2058G and A2059G) in the 23S rRNA gene of Treponema pallidum and coinfections with hepatitis B virus (HBV), hepatitis C virus (HCV) and hepatitis D virus (HDV).

Methods

FSWs were diagnosed using a rapid qualitative test and the isolates were evaluated for the presence of point mutations by real-time PCR. Blood samples with T. pallidum were tested for the presence of HBV, HCV and HDV by ELISA and confirmed by real-time PCR. The factors associated with syphili

SUBMITTER: Coelho EC 

PROVIDER: S-EPMC8436981 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature