Long-term cost-effectiveness of interventions for obesity: A mendelian randomisation study.

ABSTRACT:

Background

The prevalence of obesity has increased in the United Kingdom, and reliably measuring the impact on quality of life and the total healthcare cost from obesity is key to informing the cost-effectiveness of interventions that target obesity, and determining healthcare funding. Current methods for estimating cost-effectiveness of interventions for obesity may be subject to confounding and reverse causation. The aim of this study is to apply a new approach using mendelian randomisation for estimating the cost-effectiveness of interventions that target body mass index (BMI), which may be less affected by confounding and reverse causation than previous approaches.

Methods and findings

We estimated health-related quality-adjusted life years (QALYs) and both primary and s

SUBMITTER: Harrison S 

PROVIDER: S-EPMC8437285 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature