Decentralized vitamin C & D dual biosensor chip: Toward personalized immune system support.

ABSTRACT: Combating the ongoing COVID-19 pandemic has put the spotlight on nutritional support of the immune system through consumption of vitamins C and D. Accordingly, there are urgent demands for an effective on-the-spot multi-vitamin self-testing platform that monitors the levels of these immune-supporting micronutrients for guiding precision nutrition recommendations. Herein, we present a compact bioelectronic dual sensor chip aimed at frequent on-the-spot simultaneous monitoring of the salivary vitamin C and D dynamics. The new bioelectronic chip combines a new electrocatalytic vitamin C amperometric assay along with competitive vitamin D immunoassay on neighboring electrodes, to perform selective and cross-talk free detection of both vitamins in a 10-μL saliva sample within 25 min. The distin

SUBMITTER: Ruiz-Valdepenas Montiel V 

PROVIDER: S-EPMC8437685 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature