Genome-Wide Association Study of Seed Folate Content in Common Bean.

ABSTRACT: Plant-derived folates (Vitamin B₉) are essential components of the human diet. They provide one-carbon units that are required for the synthesis of nucleic acids and proteins, and folate deficiency is associated with numerous adverse health conditions. The development of high-folate cultivars of common bean (Phaseolus vulgaris L.) and other staple crops is an important tool to combat folate deficiency. A population of 96 P. vulgaris accessions, representing major North American market classes, was grown in 2 years in Ontario, Canada. The population was genotyped for 5,361 molecular markers with an Illumina Infinium platform. Total folate was extracted from mature seeds using the tri-enzyme extraction method and quantified based on a microbiological assay with La

SUBMITTER: Martin CJ 

PROVIDER: S-EPMC8438126 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature