Prognostic implications of histological organ involvement in retroperitoneal sarcoma.

ABSTRACT: The prognostic significance of histological organ involvement by retroperitoneal sarcoma subtype is unknown. The present study aimed to describe organ involvement across the subtypes, and the implications for survival. Patients undergoing surgery for primary retroperitoneal sarcoma at the Queen Elizabeth Hospital, Birmingham from April 2005 to September 2018 were identified retrospectively. Histological organ involvement was classed as pushing, infiltrative or neither. Univariable and multivariable Cox regression models were produced to analyse the association between histological organ involvement and both overall (OS) and recurrence-free (RFS) survival for the cohort as a whole, and by histological subtype. Data were available for a total of 197 patients, of whom 171 (86.8 per cent) had

SUBMITTER: Tyler R 

PROVIDER: S-EPMC8438256 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature