Genomic variation in captive deer mouse (Peromyscus maniculatus) populations.

ABSTRACT:

Background

Deer mice (genus Peromyscus) are the most common rodents in North America. Despite the availability of reference genomes for some species, a comprehensive database of polymorphisms, especially in those maintained as living stocks and distributed to academic investigators, is missing. In the present study we surveyed two populations of P. maniculatus that are maintained at the Peromyscus Genetic Stock Center (PGSC) for polymorphisms across their 2.5 × 10⁹ bp genome.

Results

High density of variation was identified, corresponding to one SNP every 55 bp for the high altitude stock (SM2) or 207 bp for the low altitude stock (BW) using snpEff (v4.3). Indels were detected every 1157 bp for BW or 311 bp for SM2. The average Watterson estimator for the BW and S

SUBMITTER: Lucius MD 

PROVIDER: S-EPMC8438655 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature