Paediatric sickle cell disease at a tertiary hospital in Malawi: a retrospective cross-sectional study.

ABSTRACT:

Introduction

Sickle cell disease (SCD) remains a major cause of childhood mortality and morbidity in Malawi. However, literature to comprehensively describe the disease in the paediatric population is lacking.

Methods

A retrospective review of clinical files of children with SCD was conducted. Descriptive statistics were performed to summarise the data. χ² or Fisher's exact test was used to look for significant associations between predictor variables and outcome variables (case fatality and length of hospital stay). Predictor variables that were significantly associated with outcome variables (p≤0.05) in a χ² or Fisher's exact test were carried forward for analysis in a binary logistic regression. A multivariable binary logistic regression was used to

SUBMITTER: Chimbatata CS 

PROVIDER: S-EPMC8438882 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature