Evaluating the frequency of English language requirements in clinical trial eligibility criteria: A systematic analysis using ClinicalTrials.gov.

ABSTRACT:

Background

A number of prior studies have demonstrated that research participants with limited English proficiency in the United States are routinely excluded from clinical trial participation. Systematic exclusion through study eligibility criteria that require trial participants to be able to speak, read, and/or understand English affects access to clinical trials and scientific generalizability. We sought to establish the frequency with which English language proficiency is required and, conversely, when non-English languages are affirmatively accommodated in US interventional clinical trials for adult populations.

Methods and findings

We used the advanced search function on ClinicalTrials.gov specifying interventional studies for adults with at least 1 site in the US. In

SUBMITTER: Muthukumar AV 

PROVIDER: S-EPMC8439488 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature