A systematic review of pathophysiology and management of familial hyperaldosteronism type 1 in pregnancy.

ABSTRACT:

Purpose

Familial hyperaldosteronism type 1 (FH-1) is a rare autosomal dominant form of primary aldosteronism, which features a marked phenotypic heterogeneity, ranging from mild to severe forms of arterial hypertension that can be complicated by stroke and cardiovascular events at a young age. As affected patients usually reach the fertile age, transmission of the disease to offspring is common. Notwithstanding this, reports of FH-1 in pregnancy are limited and there is a lack of treatment guidelines.

Methods and results

We searched the PubMed and EuropePMC databases with a PICO strategy to retrieve available information on management of FH-1 patients during pregnancy. We could identify seven relevant articles, which are herein reviewed.

Conclusion

Based on available

SUBMITTER: Sanga V 

PROVIDER: S-EPMC8440273 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature