Genetic architecture underlying the expression of eight α-amylase trypsin inhibitors.

ABSTRACT:

Key message

Wheat cultivars largely differ in the content and composition of ATI proteins, but heritability was quite low for six out of eight ATIs. The genetic architecture of ATI proteins is built up of few major and numerous small effect QTL. Amylase trypsin inhibitors (ATIs) are important allergens in baker's asthma and suspected triggers of non-celiac wheat sensitivity (NCWS) inducing intestinal and extra-intestinal inflammation. As studies on the expression and genetic architecture of ATI proteins in wheat are lacking, we evaluated 149 European old and modern bread wheat cultivars grown at three different field locations for their content of eight ATI proteins. Large differences in the content and composition of ATIs in the different cultivars were identified ranging from 3.7

SUBMITTER: El Hassouni K 

PROVIDER: S-EPMC8440294 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature