Efficacy of Statin Therapy in Patients with Hospital Admission for COVID-19.

ABSTRACT:

Purpose

COVID-19 is characterized by dysfunctional immune responses and metabolic derangements, which in some, lead to multi-organ failure and death. Statins are foundational lipid-lowering therapeutics for cardiovascular disease and also possess beneficial immune-modulating properties. Because of these immune-modulating properties, some have suggested their use in COVID-19. We sought to investigate the association between statin use and mortality in patients hospitalized with COVID-19.

Methods

Five thousand three hundred seventy-five COVID-19 patients admitted to Mount Sinai Health System hospitals in New York between February 27, 2020, and December 3, 2020, were included in this analysis. Statin use was classified as either non-user, low-to-moderate-intensity user, or high

SUBMITTER: Choi D 

PROVIDER: S-EPMC8440735 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature