Evaluating agreement between bodies of evidence from randomised controlled trials and cohort studies in nutrition research: meta-epidemiological study.

ABSTRACT:

Objective

To evaluate the agreement between diet-disease effect estimates of bodies of evidence from randomised controlled trials and those from cohort studies in nutrition research, and to investigate potential factors for disagreement.

Design

Meta-epidemiological study.

Data sources

Cochrane Database of Systematic Reviews, and Medline.

Review methods

Population, intervention or exposure, comparator, outcome (PI/ECO) elements from a body of evidence from cohort studies (BoE(CS)) were matched with corresponding elements of a body of evidence from randomised controlled trials (BoE(RCT)). Pooled ratio of risk ratios or difference of mean differences across all diet-disease outcome pairs were calculated. Subgroup analyses were conducted to explore factors for disa

SUBMITTER: Schwingshackl L 

PROVIDER: S-EPMC8441535 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature