The impact of estradiol on pregnancy outcomes in letrozole-stimulated frozen embryo transfer cycles.

ABSTRACT:

Objective

To assess the impact of low estradiol (E2) levels in letrozole-stimulated frozen embryo transfer (FET) cycles on pregnancy and neonatal outcomes.

Design

Retrospective cohort.

Setting

University-affiliated fertility center.

Patients

All patients who underwent letrozole-stimulated FET cycles from January 2017 to April 2020 (n = 217). The "Low E2" group was defined as those with E2 serum levels on the day of trigger <10th percentile level (E2 <91.16 pg/mL, n = 22) and the "Normal E2" group was defined as those with E2 serum levels ≥10th percentile level (E2 ≥91.16 pg/mL, n = 195).

Interventions

None.

Main outcome measures

Pregnancy outcomes including rates of clinical pregnancy, clinical miscarriage, and live birth. Neonatal outcomes includ

SUBMITTER: Zhang WY 

PROVIDER: S-EPMC8441577 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature