Closed-Loop Versus Conventional Mechanical Ventilation in COVID-19 ARDS.

ABSTRACT:

Background

Lung-protective ventilation is key in bridging patients suffering from COVID-19 acute respiratory distress syndrome (ARDS) to recovery. However, resource and personnel limitations during pandemics complicate the implementation of lung-protective protocols. Automated ventilation modes may prove decisive in these settings enabling higher degrees of lung-protective ventilation than conventional modes.

Method

Prospective study at a Swiss university hospital. Critically ill, mechanically ventilated COVID-19 ARDS patients were allocated, by study-blinded coordinating staff, to either closed-loop or conventional mechanical ventilation, based on mechanical ventilator availability. Primary outcome was the overall achieved percentage of lung-protective ventilation in closed

SUBMITTER: Wendel Garcia PD 

PROVIDER: S-EPMC8442133 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature