A pragmatic randomized trial of a primary care antimicrobial stewardship intervention in Ontario, Canada.

ABSTRACT:

Background

More than 90% of antibiotics are prescribed in primary care, but 50% may be unnecessary. Reducing unnecessary antibiotic overuse is needed to limit antimicrobial resistance. We conducted a pragmatic trial of a primary care provider-focused antimicrobial stewardship intervention to reduce antibiotic prescriptions in primary care.

Methods

Primary care practitioners from six primary care clinics in Toronto, Ontario were assigned to intervention or control groups to evaluate the effectiveness of a multi-faceted intervention for reducing antibiotic prescriptions to adults with respiratory and urinary tract infections. The intervention included provider education, clinical decision aids, and audit and feedback of antibiotic prescribing. The primary outcome was total ant

SUBMITTER: McIsaac W 

PROVIDER: S-EPMC8442308 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature