Antiseizure medications for post-stroke epilepsy: A real-world prospective cohort study.

ABSTRACT:

Background and purpose

The management of post-stroke epilepsy (PSE) should ideally include prevention of both seizure and adverse effects; however, an optimal antiseizure medications (ASM) regimen has yet been established. The purpose of this study is to assess seizure recurrence, retention, and tolerability of older-generation and newer-generation ASM for PSE.

Methods

This prospective multicenter cohort study (PROgnosis of Post-Stroke Epilepsy [PROPOSE] study) was conducted from November 2014 to September 2019 at eight hospitals. A total of 372 patients admitted and treated with ASM at discharge were recruited. Due to the non-interventional nature of the study, ASM regimen was not adjusted and followed standard hospital practices. The primary outcome was seizure recurrence

SUBMITTER: Tanaka T 

PROVIDER: S-EPMC8442594 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature