Colorectal cancer in the Linxian China Nutrition Intervention Trial: Risk factors and intervention results.

ABSTRACT:

Background

Colorectal cancer (CRC) is among the most common cancers in economically developed countries and developing world. While dietary factors are associated with risk of CRC in the West and urban China, little is known about risk or protective factors in rural China.

Methods

The Linxian General Population Nutrition Intervention Trial (NIT) cohort was established over 30 years ago to test whether daily multivitamin/mineral supplements could reduce the incidence and mortality of esophageal/gastric cardia cancer. The cohort included a total of 29,553 healthy participants 40-69 years old who were randomly assigned to supplements or placebos via a 24 fractional factorial study design. We examined risk factors for the development of CRC as well as the effects of four differe

SUBMITTER: Keskin H 

PROVIDER: S-EPMC8443060 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature