Association Between Human Papillomavirus Infection Among Pregnant Women and Preterm Birth.

ABSTRACT:

Importance

Preterm birth remains a leading cause of perinatal mortality and lifelong morbidity worldwide. The cause of most preterm births is unknown, although several infectious processes have been implicated.

Objective

To assess whether human papillomavirus (HPV) infection, a frequent infection among women of childbearing age, is associated with preterm birth.

Design, setting, and participants

The prospective HERITAGE cohort study was conducted at 3 academic hospitals in Montreal, Québec, Canada, among 899 pregnant women recruited between November 8, 2010, and October 16, 2016. Follow-up was completed on June 15, 2017. Statistical analysis was conducted from February 6, 2020, to January 21, 2021.

Exposures

Vaginal HPV DNA detection in the first and third trim

SUBMITTER: Niyibizi J 

PROVIDER: S-EPMC8444026 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature