Ontology highlight
ABSTRACT:
SUBMITTER: Fransen LFH
PROVIDER: S-EPMC8444090 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Fransen Leonie F H LFH Leonard Martin O MO
Toxicology in vitro : an international journal published in association with BIBRA 20210609
Paraquat (PQ) is a redox cycling herbicide known for its acute toxicity in humans. Airway parenchymal cells have been identified as primary sites for PQ accumulation, tissue inflammation and cellular injury. However, the role of immune cells in PQ induced tissue injury is largely unknown. To explore this further, primary cultures of human CD34+ stem cell derived macrophages (MC<sup>cd34</sup>) and dendritic cells (DC<sup>cd34</sup>) were established and characterised using RNA-Seq profiling. The ...[more]