Multimorbidity and mortality in an older, rural black South African population cohort with high prevalence of HIV findings from the HAALSI Study.

ABSTRACT:

Objectives

Multimorbidity is associated with mortality in high-income countries. Our objective was to investigate the relationship between multimorbidity (≥2 of the following chronic medical conditions: hypertension, diabetes, dyslipidaemia, anaemia, HIV, angina, depression, post-traumatic stress disorder, alcohol dependence) and all-cause mortality in an older, rural black South African population. We further investigated the relationship between HIV multimorbidity (HIV as part of the multimorbidity cluster) and mortality, while testing for the effect of frailty in all models.

Design

Population cohort study.

Setting

Agincourt subdistrict of Mpumalanga province, South Africa.

Participants

4455 individuals (54.7% female), aged ≥40 years (median age 61 years, IQR

SUBMITTER: Wade AN 

PROVIDER: S-EPMC8444254 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature