Left atrial appendage occlusion in the UK: prospective registry and data linkage to Hospital Episode Statistics.

ABSTRACT:

Aims

Non-valvular atrial fibrillation (AF) greatly increases the risk of ischaemic stroke. For people with contraindications to oral anticoagulation, left atrial appendage occlusion (LAAO) provides a non-pharmacological management alternative. The aim of this study was to measure the procedural safety and longer-term effectiveness of LAAO for AF in a UK setting.

Methods and results

This was a prospective, single-armed registry of patients with AF for whom anticoagulation was unsuitable. Registry data were collected between October 2014 and April 2018 and linked to routine data sources for follow-up. Data from 583 LAAO procedures were entered into the registry, of which 537 (from 525 patients) were eligible for inclusion (median CHA2DS2-VASc score 4). A closure device was suc

SUBMITTER: Willits I 

PROVIDER: S-EPMC8445086 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature